SS-OCT vs SD-OCT: BioPhotonics April issue

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In the April 2018 issue of BioPhotonics, our own Dr. Nishant Mohan reviews the state of the art in swept source and spectral domain OCT to see how recent developments in each technology are creating interesting tradeoffs for clinicians and researchers. Recent developments in SD-OCT have put it back on the map for applications that require high speeds and deeper penetration while maintaining high resolution and lower costs. James Fujimoto of MIT and Steven Adie of Cornell University weigh in.

“In ophthalmology, SD-OCT has the advantage that it achieves higher resolution than SS-OCT. Advances in line scan camera and spectrometer technologies have more than doubled imaging speed, while also reducing sensitivity roll off. The high speeds achieved by state-of-the-art line scan cameras and SD-OCT will be especially important for volumetric imaging applications and en face OCT, where each pixel in the en face image is generated from an axial scan in the volumetric data set.” 

– James Fujimoto, MIT

Wide-field image of human retina, courtesy of James Fujimoto, MIT
Wide-field, high-resolution image of human retina acquired using a Wasatch Photonics Cobra-S OCT spectrometer. Imaging parameters: no averaging, 128 kHz A-line rate, expected axial resolution of 3 μm in tissue. Courtesy of James Fujimoto, MIT. [As seen in BioPhotonics magazine, April 2018]

Read the full article in BioPhotonics online